骨关节炎治疗新发现

骨关节炎是一种失控的炎症，会导致疼痛、僵硬、活动能力丧失，并逐渐使负责防止骨骼相互摩擦的软骨消失。最近的一项科学发现可能会改变一种最常见的老年疾病——骨关节炎的未来，它远不止是关节软骨的“磨损”。这种药物也在从接受过膝盖手术的患者身上获取的人体软骨上奏效。如果人体试验成功，未来可能会有软骨再生疗法，更少的手术和假体，以及更高的生活质量和活动能力。 specializing in traumatology, aesthetics, nutrition, and anti-aging medicine, explained that inside the joints there are cells that are responsible for our defense, and when everything is going well, they help repair damage. However, in osteoarthritis, these cells get confused and release inflammatory substances that damage the joint. 'More studies in people, safety tests, and time are needed to confirm the results,' said the doctor. A recent study from Stanford University discovered that in joints with osteoarthritis, a protein called 15-PGDH accumulates, which acts as a 'switch' that increases inflammation, prevents cartilage from repairing itself, and accelerates the destruction of the joint. This protein is responsible for the disease to progress, but if it is blocked, it causes the cartilage to grow again, which was evidenced by an experimental drug that blocks 15-PGDH and was tested on mice. Montel commented that this is not just stopping the disease, but reversing it. Not yet. Science has found the 'button' that starts the destruction and the way to turn it off. 'Does this mean that the cure already exists?'